电话:
传真:-8008
QQ:3007536035
地址:上海市闵行区兴梅路485号 XingMei Rd 485ShanghaiChina
该系统有两个型号可供选择:Feedback 和 StandAlone
· 可由电脑和主机控制; · 击打棒以设定的转速干扰动物睡眠; · 可以通过程序编制改变方向,以减少睡眠剥夺的动物对环境的适应; · 系统可提供食物、水和活动场所; · 动物笼分大鼠笼和小鼠笼两种款式;
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根据需要,还可以选择转棒式睡眠剥夺仪、水槽式睡眠剥夺箱,来开展相关实验:
转棒式睡眠剥夺仪的产品特点:
· 具有四种工作模式:常开、定时、间歇、正反转;
· 转棒转动温和,不会对动物造成任何机械损伤;
· 定时模式可设置干扰棒转动的时间;
· 间歇模式可分别调节转动时间和停止时间;
· 正反转模式,可以定时设置干扰棒的运转方向;
· 转棒高度可调,减少垫料的影响;
· 根据实验需求,选配大鼠型、小鼠型活动笼;
· 金年会也可以提供定制化改进服务;
型号:YAN-239
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可根据需要,选择水槽式睡眠剥夺箱:
型号:SY-M3100,小鼠,6个平台
SY-M3040,小鼠,40个平台
SY-R3020,大鼠,15个平台
更多型号,请来电咨询
小鼠的水槽式睡眠和疲劳剥夺实验正在进行中
参考文献:
1. Cordeira, J., Kolluru, S.S., Rosenblatt, H., Kry, J., Strecker, R.E., McCarlet, R.W. (2017). Learning and memory are impaired in the object recognition task during metestrus/diestrus and after sleep deprivation. Behavioural Brain Research, 339, 124-129. doi: 10.1016/j.bbr.2017.11.033
2. Hines, D.J., Schmitt, L.I., Hines, R.M., Moss, S.J., & Haydon, P.G. (2013). Antidepressant effects of sleep deprivation require astrocyte-dependent adenosine mediated signaling. Translational Psychiatry, 3, e212. doi: 10.1038/tp.2012.136
3. Lee, D., Lee, S., & Sohn, D. (2016). MP86-19 effect of sleep deprivation on hormonal axis and erectile function. Journal of Urology, 195(4), e1113. doi:10.1016/j.juro.2016.02.2327
4. Lee, D.S., Sohn, D.W., Yoon, B.I., & Yoo, J.M. (2017). 383 effect of sleep deprivation on hormonal axis and erectile function. Journal of Sexual Medicine, 14(1), S113-S114. doi: 10.1016/j.jsxm.2016.11.264
5. Naidoo, N., Davis, J.G., Zhu, J., Yabumoto, M., Singletary, K., Brown, M., … & Baur, J.A. (2014). Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell, 13(1), 131-141. doi: 10.1111/acel.12158
6. Schmidt, M.A. & Wisor, J.P. (2012). Interleukin 1 receptor contributes to methamphetamine- and sleep deprivation-induced hypersomnolence. Neuroscience Letters, 513(2), 209-213. doi: 10.1016/j.neulet.2012.02.040
7. Ward, C.P., Wooden, J.I., & Kieltyka, R. (2017). Effects of sleep deprivation on spatial learning and memory in juvenile and young adult rats. Psychology & Neuroscience, 10(1), 109-116. doi: 10.1037/pne0000075
8. Wooden, J., Pido, J., Mathews, H., Kieltyka, R., Montemayor, B., & Ward, C. (2014). Sleep deprivation impairs recall of social transmission of food preference in rats. Nature and Science of Sleep, 2014(6), 129-135. doi: 10.2147/NSS.S68611
9. Duncan, M. J., L. E. Guerriero, K. Kohler, L. E. Beechem, B. D. Gillis, F. Salisbury, C. Wessel, J. Wang, S. Sunderam, A. D. Bachstetter, B. F. O’Hara and M. P. Murphy, 2022. Chronic Fragmentation of the Daily Sleep-Wake Rhythm Increases Amyloid-beta Levels and Neuroinflammation in the 3xTg-AD Mouse Model of Alzheimer’s Disease. Neuroscience 481: 111-122.
10. Robinson-Junker, A., O’Hara, B., Durkes, A., Gaskill, B., 2019. Sleeping through anything: The effects of unpredictable disruptions on mouse sleep, healing, and affect. PloS one 14, e0210620.
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