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脑立体定位仪

小鼠脑立体定位仪

时间:2021-12-15来源:本站作者:金年会仪器

详细介绍

金年会仪器自主研发脑立体定位仪十四年,适用于大鼠、小鼠等实验动物,经典十字操作臂实现精准定位,精度可达10微米,特制螺纹精密螺杆,稳固不晃动实现对特定脑区的精确定位,是神经环路研究、神经系统性疾病、神经药理等领域内的重要研究设备,广泛面向全国各大科研院校,医院,高新企业,药企,医疗机构等科研单位。小鼠脑立体定位仪是专门为小鼠准备的定位仪,是为敲除基因小鼠实验和转基因小鼠实验设计的。它是一款体积较小和比较经济的定位设备。


主要配置:包含3轴左手操作臂,小鼠嘴夹和齿杆,双面耳杆,和一个角夹探头支架。


小鼠专用型的脑立体定位仪采用了三大技术来牢固固定小鼠头部:

1、轻质的聚甲醛树脂耳棒,前端逐渐变细;

2、特殊设计的下颌夹持器;

3、非植入性橡胶头;


耳棒的高度可以独立调节,垂直方向的刻度采用了激光雕刻技术,能够非常新晰的读出耳棒的高度。

1. 可以同时定位新生鼠和小型啮齿类动物

2. 底座尺寸:25cmx25cm

3. 兼容气体麻醉机

4. 耳棒和牙棒的高度调整适合10-75g小鼠

5. Delrin®材料的耳棒,更适合于小鼠实验操作

6. 三维操作臂可以精确定位

7. 支持双操作臂工作模式

8. 可选数显模式

9. 可选全自动模式

10. 精确度标准型100um,数显型10um


根据需求不同,有多种不同的型号可供选择:单臂型,双臂型,数显型



标准型小鼠脑定位仪  型号:SA-100


便携式小鼠定位仪  型号:SA-103 


数显型小鼠脑定位仪  型号:SA-150




双臂型小鼠脑定位仪   型号:SA-113



相关配件及可选配件:


大鼠门牙固定适配器

小鼠固定适配器


 


电极夹持器

电极、螺帽、注射器夹持器


电极、注射器夹持器


微量注射器


微量注射泵


颅骨钻


小动物脑立体定位仪部分参考文献:
1. Albéri, L., Lintas, A., Kretz, R., Schwaller, B., & Villa, A. E. (2013). The calcium-binding protein parvalbumin modulates the firing 1 properties of the reticular thalamic nucleus bursting neurons. Journal of neurophysiology, 109(11), 2827-2841.
2. Sonati, T., Reimann, R. R., Falsig, J., Baral, P. K., O’Connor, T., Hornemann, S., Aguzzi, A. (2013). The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 501(7465), 102-106.
3. Ali, I., O’Brien, P., Kumar, G., Zheng, T., Jones, N. C., Pinault, D., O’Brien, T. J. (2013). Enduring Effects of Early Life Stress on Firing Patterns of Hippocampal and Thalamocortical Neurons in Rats: Implications for Limbic Epilepsy. PLOS ONE, 8(6), e66962.
4. Bell, L. A., Bell, K. A., & McQuiston, A. R. (2013). Synaptic Muscarinic Response Types in Hippocampal CA1 Interneurons Depend on Different Levels of Presynaptic Activity and Different Muscarinic Receptor Subtypes. Neuropharmacology.
5. Bolzoni, F., Bączyk, M., & Jankowska, E. (2013). Subcortical effects of transcranial direct current stimulation (tDCS) in the rat. The Journal of Physiology.
6. Bolzoni, F., Bączyk, M., & Jankowska, E. (2013). Subcortical effects of transcranial direct current stimulation (tDCS) in the rat. The Journal of Physiology.
7. Babaei, P., Tehrani, B. S., & Alizadeh, A. (2013). Effect of BDNF and adipose derived stem cells transplantation on cognitive deficit in Alzheimer model of rats. Journal of Behavioral and Brain Science, 3, 156-161.
8. Gilmartin, M. R., Miyawaki, H., Helmstetter, F. J., & Diba, K. (2013). Prefrontal Activity Links Nonoverlapping Events in Memory. The Journal of Neuroscience, 33(26), 10910-10914.
9. Feng, L., Sametsky, E. A., Gusev, A. G., & Uteshev, V. V. (2012). Responsiveness to nicotine of neurons of the caudal nucleus of the solitary tract correlates with the neuronal projection target. Journal of Neurophysiology, 108(7), 1884-1894.
10. Clarner, T., Diederichs, F., Berger, K., Denecke, B., Gan, L., Van der Valk, P., Kipp, M. (2012). Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions. Glia, 60(10), 1468-1480.
11. Girardet, C., Bonnet, M. S., Jdir, R., Sadoud, M., Thirion, S., Tardivel, C., Troadec, J. D. (2011). Central inflammation and sickness-like behavior induced by the food contaminant deoxynivalenol: A PGE2-independent mechanism.Toxicological Sciences, 124(1), 179-191.
12. Hruška-Plocháň, M., Juhas, S., Juhasova, J., Galik, J., Miyanohara, A., Marsala, M., Motlik, J. (2010). A27 Expression of the human mutant huntingtin in minipig striatum induced formation of EM48+ inclusions in the neuronal nuclei, cytoplasm and processes. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A9.
13. Brooks, S., Jones, L., & Dunnett, S. B. (2010). A29 Frontostriatal pathology in the (C57BL/6J) YAC128 mouse uncovered by the operant delayed alternation task. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A10.
14. Yu, L., Metzger, S., Clemens, L. E., Ehrismann, J., Ott, T., Gu, X., Nguyen, H. P. (2010). A28 Accumulation and aggregation of human mutant huntingtin and neuron atrophy in BAC-HD transgenic rat. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A9.
15. Baxa, M., Juhas, S., Pavlok, A., Vodicka, P., Juhasova, J., Hruška-Plocháň, M., Motlik, J. (2010). A26 Transgenic miniature pig as an animal model for Huntington’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A8-A9.




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